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Volume 335, Issue 2

October 1998

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Cover Image

Cover Image
Front Matter
Table of Contents

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research communications
Research articles

Review articles

Genetic engineering in mice: impact on insulin signalling and action

Betty LAMOTHE; Anne BAUDRY; Pierrette DESBOIS; Lucianne LAMOTTE; Danielle BUCCHINI; Pierre DE MEYTS; Rajiv L. JOSHI

Biochem J (1998) 335 (2): 193–204.

Abstract

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Research communications

The cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targeting

Luke H. CHAMBERLAIN; Robert D. BURGOYNE

Biochem J (1998) 335 (2): 205–209.

Abstract

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Research articles

Circe's haemoglobins, pig–human hybrids: functional characterization and structural considerations

Maria T. SANNA; Bruno GIARDINA; Mariagiuseppina PELLEGRINI; Alessandra OLIANAS; Irene MESSANA; Massimo CASTAGNOLA; Marcella CORDA

Biochem J (1998) 335 (2): 211–216.

Abstract

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Purification and characterization of autophagosomes from rat hepatocytes

Per Eivind STRØMHAUG; Trond Olav BERG; Monica FENGSRUD; Per O. SEGLEN

Biochem J (1998) 335 (2): 217–224.

Abstract

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The insertion of human apolipoprotein H into phospholipid membranes: a monolayer study

Shao-Xiong WANG; Guo-ping CAI; Sen-fang SUI

Biochem J (1998) 335 (2): 225–232.

Abstract

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Oxidation of DNA bases, deoxyribonucleosides and homopolymers by peroxyl radicals

Tiberiu SIMANDAN; Jing SUN; Thomas A. DIX

Biochem J (1998) 335 (2): 233–240.

Abstract

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Stimulation of gene expression in neonatal rat ventricular myocytes by Ras is mediated by Ral guanine nucleotide dissociation stimulator (Ral.GDS) and phosphatidylinositol 3-kinase in addition to Raf

Stephen J. FULLER; Stephen G. FINN; Julian DOWNWARD; Peter H. SUGDEN

Biochem J (1998) 335 (2): 241–246.

Abstract

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Modulation of RGD sequence motifs regulates disintegrin recognition of αIIbβ3 and α5β1 integrin complexes

Salman RAHMAN; Alex AITKEN; Geraldine FLYNN; Caroline FORMSTONE; Geoffrey F. SAVIDGE

Biochem J (1998) 335 (2): 247–257.

Abstract

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The mouse ADP-ribosylation factor-like 4 gene: two separate promoters direct specific transcription in tissues and testicular germ cell

Stephan JACOBS; Annette SCHÜRMANN; Walter BECKER; Tobias M. BÖCKERS; Neal G. COPELAND; Nancy A. JENKINS; Hans-Georg JOOST

Biochem J (1998) 335 (2): 259–265.

Abstract

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Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle

Daniel GOLDMAN; Mohan K. SAPRU; Scott STEWART; Joshua PLOTKIN; Towia A. LIBERMANN; Bohdan WASYLYK; Kunliang GUAN

Biochem J (1998) 335 (2): 267–275.

Abstract

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Functional analysis of the T-cell-restricted protein tyrosine kinase Txk

Jonathan H. ELLIS; Roger P. M. SUTMULLER; Martin J. SIMS; Susan COOKSLEY

Biochem J (1998) 335 (2): 277–284.

Abstract

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The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts

Petra LEPPIMÄKI; Robert KRONQVIST; J. Peter SLOTTE

Biochem J (1998) 335 (2): 285–291.

Abstract

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Effect of nutritional state on the formation of a complex involving insulin receptor IRS-1, the 52 kDa Src homology/collagen protein (Shc) isoform and phosphatidylinositol 3′-kinase activity

Joëlle DUPONT; Michel DEROUET; Jean SIMON; Mohammed TAOUIS

Biochem J (1998) 335 (2): 293–300.

Abstract

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Evidence for the presence of multiple forms of Sph kinase in human platelets

Yoshiko BANNO; Makiko KATO; Akira HARA; Yoshinori NOZAWA

Biochem J (1998) 335 (2): 301–304.

Abstract

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Characterization of the hypertonically induced tyrosine phosphorylation of erythrocyte band 3

Giampaolo MINETTI; Claudio SEPPI; Annarita CIANA; Cesare BALDUINI; Philip S. LOW; Augusta BROVELLI

Biochem J (1998) 335 (2): 305–311.

Abstract

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Energy requirements for two aspects of phospholipid metabolism in mammalian brain

A. David PURDON; Stanley I. RAPOPORT

Biochem J (1998) 335 (2): 313–318.

Abstract

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Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding

Peter MACHEROUX; Ernst SCHÖNBRUNN; Dmitri I. SVERGUN; Vladimir V. VOLKOV; Michel H. J. KOCH; Stephen BORNEMANN; Roger N. F. THORNELEY

Biochem J (1998) 335 (2): 319–327.

Abstract

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Mammalian cell polyamine homeostasis is altered by the radioprotector WR1065

John L. A. MITCHELL; Jennifer RUPERT; Aviva LEYSER; Gary G. JUDD

Biochem J (1998) 335 (2): 329–334.

Abstract

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The effects of a Ca2+ chelator and heavy-metal-ion chelators upon Ca2+ oscillations and activation at fertilization in mouse eggs suggest a role for repetitive Ca2+ increases

Yvonne LAWRENCE; Jean Pierre OZIL; Karl SWANN

Biochem J (1998) 335 (2): 335–342.

Abstract

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Susceptibility towards intramolecular disulphide-bond formation affects conformational stability and folding of human basic fibroblast growth factor

David ESTAPÉ; Joop van den HEUVEL; Ursula RINAS

Biochem J (1998) 335 (2): 343–349.

Abstract

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Phosphatidylinositol 4-kinase, but not phosphatidylinositol 3-kinase, is present in GLUT4-containing vesicles isolated from rat skeletal muscle

S⊘ren KRISTIANSEN; Toolsie RAMLAL; Amira KLIP

Biochem J (1998) 335 (2): 351–356.

Abstract

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Voltammetric studies of the reactions of iron–sulphur clusters ([3Fe-4S] or [M3Fe-4S]) formed in Pyrococcus furiosus ferredoxin

Sarah E. J. FAWCETT; David DAVIS; Jacques L. BRETON; Andrew J. THOMSON; Fraser A. ARMSTRONG

Biochem J (1998) 335 (2): 357–368.

Abstract

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Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment

Mar PÉREZ; Francisco WANDOSELL; Camilo COLAÇO; Jesús AVILA

Biochem J (1998) 335 (2): 369–374.

Abstract

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Secondary structure analysis of the putative membrane-associated domains of the inward rectifier K+ channel ROMK1

Stephen P. BRAZIER; Bala. RAMESH; Parvez I. HARIS; David C. LEE; Surjit K. S. SRAI

Biochem J (1998) 335 (2): 375–380.

Abstract

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Human MUC5AC mucin dimerizes in the rough endoplasmic reticulum, similarly to the MUC2 mucin

Noomi ASKER; Magnus A. B. AXELSSON; Sven-Olof OLOFSSON; Gunnar C. HANSSON

Biochem J (1998) 335 (2): 381–387.

Abstract

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Cytosolic deglycosylation process of newly synthesized glycoproteins generates oligomannosides possessing one GlcNAc residue at the reducing end

Sandrine DUVET; Odette LABIAU; Anne-Marie MIR; Daniel KMIÉCIK; Sharon S. KRAG; André VERBERT; René CACAN

Biochem J (1998) 335 (2): 389–396.

Abstract

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Phosphatidylinositol 3′-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase

Keith A. CENGEL; Rosanne E. KASON; Gregory G. FREUND

Biochem J (1998) 335 (2): 397–404.

Abstract

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Glucose induces expression of stearoyl-CoA desaturase in 3T3-L1 adipocytes

Brynn H. JONES; Melissa K. STANDRIDGE; Kate J. CLAYCOMBE; Pamela J. SMITH; Naïma MOUSTAÏD-MOUSSA

Biochem J (1998) 335 (2): 405–408.

Abstract

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Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 Å resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate

Lloyd F. MACKENZIE; Gerlind SULZENBACHER; Christina DIVNE; T. Alwyn JONES; Helle F. WÖLDIKE; Martin SCHÜLEIN; Stephen G. WITHERS; Gideon J. DAVIES

Biochem J (1998) 335 (2): 409–416.

Abstract

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Atypical protein kinase Cλ binds and regulates p70 S6 kinase

Kazunori AKIMOTO; Masaaki NAKAYA; Tomoyuki YAMANAKA; Junpei TANAKA; Shin-ichi MATSUDA; Qing-Ping WENG; Joseph AVRUCH; Shigeo OHNO

Biochem J (1998) 335 (2): 417–424.

Abstract

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Involvement of a local Fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes

Thomas KIETZMANN; Torsten PORWOL; Karl ZIEROLD; Kurt JUNGERMANN; Helmut ACKER

Biochem J (1998) 335 (2): 425–432.

Abstract

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Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

Subburaj ILANGUMARAN; Daniel C. HOESSLI

Biochem J (1998) 335 (2): 433–440.

Abstract

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Purification and biochemical characterization of a poly(ADP-ribose) polymerase-like enzyme from the thermophilic archaeon Sulfolobus solfataricus

Maria Rosaria FARAONE-MENNELLA; Agata GAMBACORTA; Barbara NICOLAUS; Benedetta FARINA

Biochem J (1998) 335 (2): 441–447.

Abstract

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Identification of Glu-277 as the catalytic nucleophile of Thermoanaerobacterium saccharolyticum β-xylosidase using electrospray MS

David J. VOCADLO; Lloyd F. MACKENZIE; Shouming HE; Gregory J. ZEIKUS; Stephen G. WITHERS

Biochem J (1998) 335 (2): 449–455.

Abstract

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Sialomucin complex at the rat ocular surface: a new model for ocular surface protection

Shari A. PRICE-SCHIAVI; Daniel MELLER; Xin JING; Jennifer MERRITT; Maria E. CARVAJAL; Scheffer C. G. TSENG; Kermit L. CARRAWAY

Biochem J (1998) 335 (2): 457–463.

Abstract

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